課程資訊
課程名稱
 腦功能影像實驗設計與分析
Functional Brain Imaging Experimental Design and Analysis 
開課學期
 105-1 
授課對象
 腦與心智科學研究所  
授課教師
 吳恩賜 
課號
 GIBMS7112 
課程識別碼
 454 M0310 
班次
 01 
學分
 3 
全/半年
 半年 
必/選修
 選修 
上課時間
 星期二6,7,8(13:20~16:20) 
上課地點
 基醫1503 
備註
 上課地點為基醫大樓B1小班教室05室。與曾凱元、曾明宗、曾文毅合開
限碩士班以上 或 限本系所學生(含輔系、雙修生)
總人數上限：12人 
Ceiba 課程網頁
 http://ceiba.ntu.edu.tw/1051GIBMS7112_01 
課程簡介影片
 
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課程概述

This course will provide theoretical and practical training on functional magnetic resonance imaging (fMRI) experimental design, data preprocessing, and analysis. The main fMRI data analysis programs used in this course will be Statistical Parametric Mapping 8 (SPM8) running on Matlab. Other tools will be introduced as needed. Positron Emission Tomography (PET) imaging will also be introduced as another functional brain imaging tool.

Prerequisites: Course participants must be graduate students of the Graduate Institute of Brain and Mind Sciences. Graduate students external to this institute may be admitted with approval from their advisors as well as the course instructors. Students should bring their own computers with their own copy of Matlab installed. If students are using Windows machines, Cygwin (http://www.cygwin.com/; all packages) must also be installed for FSL.

Week Date Topic Lecturer
1 2015/9/18 Basic MR Physics Isaac Wen-Yih Tseng
2 2015/9/25 fMRI Principles of Measuring Neural Activity Ming-Tsung Tseng
3 2015/10/2 fMRI Principles of Experimental Design Joshua Oon Soo Goh
4 2015/10/9 National Day -
5 2015/10/16 Presenting Stimuli with E-Prime Joshua Oon Soo Goh
6 2015/10/23 Presenting Stimuli with Presentation Ming-Tsung Tseng
7 2015/10/30 Visit to Prisma Ming-Tsung Tseng
8 2015/11/6 fMRI Data Preprocessing Joshua Oon Soo Goh
9 2015/11/13 Probability, t-test, ANOVA Joshua Oon Soo Goh
10 2015/11/20 Multiple Regression Joshua Oon Soo Goh
11 2015/11/27 fMRI Data First-level Statistical Analysis Joshua Oon Soo Goh
12 2015/12/4 fMRI Data Analysis: Higher-level Analysis Joshua Oon Soo Goh
13 2015/12/11 Regions-Of-Interest Analysis Joshua Oon Soo Goh
14 2015/12/18 PET Imaging Kai-Yuan Tzen
15 2015/12/25 Student Project Presentations -
16 2016/1/1 New Year’s Day -
17 2016/1/8 Break for examination period -
 

課程目標
 待補 
課程要求
 Students will be given a sample fMRI dataset to analyze and submit a research report based on their analysis. The report must be in a standard research manuscript format consisting of a title, abstract, introduction with background and hypothesis, methods, results, discussion, and references. The report must be in English, APA format, Times New Roman font, 12 pt font size, double-spaced, and no more than 30 pages. The report is due 1 week after the last class by 1700hrs. 
預期每週課後學習時數
  
Office Hours
  
指定閱讀
  
參考書目
 Functional Magnetic Resonance Imaging, Second Edition (2004) by Scott A. Huettel, Allen W. Song, Gregory McCarthy, Sinauer Associates, Sunderland, MA, USA. 
評量方式
(僅供參考)
    
課程進度
週次
日期
單元主題
Week 1
 9/13  Basic MR Physics (Isaac Wen-Yih Tseng) 
Week 2
 9/20  Principles of Measuring Neural Activity (Ming-Tsung Tseng) 
Week 3
 9/27  Principles of fMRI Experimental Design 
Week 4
 10/04  Principles of fMRI Experimental Design 
Week 5
 10/11  Presenting Stimuli with E-Prime 
Week 6
 10/18  fMRI Data Preprocessing: Matlab, SPM8, Motion Correction, Slice-Time Correction, Coregistration. 
Week 7
 10/25  Visit to Prisma (Ming-Tsung Tseng) 
Week 8
 11/01  Presenting Stimuli with Presentation (Ming-Tsung Tseng) 
Week 9
 11/08  fMRI Data Preprocessing: Normalization – 12D Affine Transform, Segmentation, DARTEL, SST. 
Week 10
 11/15  Probability, t-test, ANOVA 
Week 11
 11/22  Multiple Regression 
Week 12
 11/29  fMRI Data First-level Statistical Analysis 
Week 13
 12/06  fMRI Data Analysis: Higher-level Analysis 
Week 14
 12/13  Regions-Of-Interest Analysis 
Week 15
 12/20  Analyzing Brain Images in Matlab: Coding Approaches 
Week 16
 12/27  Functional Connectivity Analysis 
Week 17
 1/03  Student Project Presentations